Columns "Desepta®" and "Desepta®-LPS" for the treatment of sepsis

Column "Desepta" – a domestic analogue with additional functions, replacing the column CytoSorb (USA), is applicable in all cases when it is necessary to remove excess cytokines, inflammatory mediators from the blood and other physiological fluids, and to reduce the level of endotoxins. Column "Desepta-LPS" – a domestic analogue with additional functions, replacing columns Toraymyxin-PMX-20R (Japan) and Alteco-LPS (Sweden), – is applicable for the selective removal of endotoxins (LPS) from blood and other physiological fluids and reducing the concentration of cytokines … Scope: resuscitation, toxicology, surgery, combustiology, obstetrics and gynecology, pediatrics, extreme, military field medicine, disaster medicine. capacity and low flow resistance. In this case, the total volume of the column is 2 times less than usual, because a patented spatial filter with 96% porosity retains a fine sorbent fraction from 180 microns, which is in an isotonic solution (0.9% NaCl solution). The adsorption surface of hemosorbent in the column reaches 96,000 m2 and exceeds the adsorption surface of hemosorbents (granules 0.25 – 1.5 mm) contained in typical columns. Maximum working pressure – 400 mm Hg, maximum allowable – 500 mm Hg. The pressure difference at the inlet and outlet of the column does not exceed 100 mm Hg at a blood perfusion rate of 120 ml / min. The design of the column provides increased safety of use. Completely excludes the ingress of air bubbles into the sorbent without shaking it and other additional manipulations when connecting to the extracorporeal circuit, filling and perfusion of blood. Provides its uniform contact with the sorbent throughout the volume of the column without the formation of stagnant zones and "channeling" the blood flow. Small air bubbles, which can form during blood perfusion, accumulate in the upper part of the column, which is structurally an air trap, preventing them from entering the extracorporeal circuit and reducing the risk of air embolism, regardless of the presence of an air trap in the blood line. The direction of blood flow in the column is from top to bottom. The blood inlet and outlet are at the bottom of the column. The column is available with large (1/2 'DIN) Luer-Lock connectors for direct connection to the lines of artificial kidney devices: Multifiltrate, PrismaFlex, Octo-Nova, Innova Hospal, Aquarius, etc. The design of the column provides connection to the lines, air removal and flushing without additional adapters and adapters. Read more … The column works as part of the extracorporeal circuit of any perfusion devices for hemosorption, incl. using roller pumps: Unirol, UAG, N1, etc., devices for plasmapheresis, hemodialysis (Multifiltrate, PrismaFlex, Octo-Nova, Innova Hospal, Aquarius, etc.). Both separately and in conjunction with other mass transfer devices, for example, a hemofilter, when it is serially connected using the supplied adapters (adapters) with a hemosorption column for more effective relief of SIRS by simultaneous hemosorption (adsorption) and hemofiltration. Those. specifications Dimensions: 40 x 185 mm Weight: 190 g Capacity: 150 ml Volume of filling with blood: 40 ml Adsorption surface: 84-96 thousand sq. endotoxin capacity: from 7,000 to 790,000 units.