Plasma filter "Hemos-PFS"

Plasma filter "Gemos-PFS" – the main element of the filtration technology of medical and donor plasmapheresis – is designed to extract plasma from blood. The Hemos-PFS plasma filter also showed the possibility of using a new filtration method for washing cryopreserved erythrocytes, which is more gentle than the traditional centrifugal method and provides an increased yield of full-fledged erythrocytes for transfusion to patients. Unlike the designs of domestic flat-frame plasma filters PFM-800/500 , PFM 01-TT ("Rosa"), and imported hollow fiber plasma filters, "Gemos-PFS" has the following advantages. Several times less weight, dimensions, volume of filling with blood and a small area of blood contact with a highly porous hydrophilized membrane with increased hemocompatibility and low affinity for plasma proteins and lipids. The Hemos-PFS plasma filter provides a high filtration rate of high-quality plasma: 15-25 ml / min. Works for at least 3-5 hours at low and high rates of blood perfusion: 30-120 ml / min, high constant transmembrane pressure – up to 250 – 280 mm Hg. and pulse (<3 sec) pressure in the blood circuit up to 400 mm Hg. During long-term operation, it does not require flushing, because the initial plasma filtration performance decreases slightly, less than 8%. Heparin is used as an anticoagulant. If necessary, solutions containing sodium citrate. The Gemos-PFS plasma filter has a transparent cylindrical body, Luer-Lock screw connections, and is compatible with all domestic (Gemos-PF, Gemofeniks, Gemma) and imported pipelines. (Multifiltrate, PrismaFlex, Octo-Nova, Fresenius 4008, 5008, Innova Hospal, Aquarius, "Hemofer-1", etc.) devices for membrane plasmapheresis. Air displacement and initial filling with saline in comparison with domestic plasma filters (PFM-800/500 , PFM 01-TT ("Dew")) occurs completely, without turning and shaking, because blood and plasma fittings are located along the axis of the spiral plasma filter and the direction of blood and plasma flow. It is produced as a separate item or as a part of the Plasmosettm closed consumable set for the Gemos-PF plasmapheresis apparatus that does not require assembly. Spiral plasma filter "Gemos-PFS" – equivalent replacement for: – imported hollow fiber plasma filters: TPE (PF) -1000/2000, 3M PlasCure 03, Haemoselect, etc. More details … – domestic flat-frame plasma filters PFM-800/500, PFM-01 -TT ("Rosa"), "Gemos-PFS" spiral plasma filter is approved by Roszdravnadzor for use in medical practice (RU No. RZN 2013/713 of July 16, 2013) and is produced in series. Those. specifications Medical and technical characteristics of the Hemos-PFS spiral plasma filter Spiral design Blood filling volume, no more than 5 ml Residual plasma volume in the filter, no more than 3 ml Filter membrane: – filter layer thickness, no more than 10 microns – average pore size, no more than 0, 4 μm – porosity, ± 5%, not less than 80% – surface area, ± 5%, not less than 280 cm2 – material – hydrophilic – contact angle, Ɵ, not more than 38 degrees Minimum blood perfusion rate, 20 ml / min Maximum perfusion rate blood pressure, 120 ml / min Optimum constant pressure at the filter inlet ± 15%, 200 mm Hg Maximum permissible constant pressure at the filter inlet ± 15%, 250 mm Hg Maximum pulse (≤ 3 sec) pressure at the filter inlet ± 50 mm Hg – 350 mm Hg Pressure drop at the inlet and outlet of the filter, ± 15%, not more than 80 mm Hg, Plasma output from the inlet blood flow, 25 – 35%, Decrease in productivity in 1 hour work, no more than 8%, Duration of work – not limited free hemoglobin, no more than 10 mg%, Anticoagulants used to stabilize the blood before the plasma filter heparin or solutions containing sodium citrate Filter body cylindrical, transparent, rigid Sterilization radiation The filter construction materials are pyrogen-free, non-toxic, hemocompatible, hypoallergenic and parallarisation of the blood, and the blood is injected into the direction of the plasma from blood and plasma chambers by liquid displacement from bottom to top, without changing the position of the filter Type of design – a separate product – a single whole with the line Type of fittings connections Luer-lock Overall dimensions (without fittings), mm, no more than 40 x 35 Overall dimensions (with fittings and removable caps), no more than 40 x 130 mm, Weight, no more than 25 g, Shelf life, no less than 3 years